|
KMID : 0043320120350101739
|
|
Archives of Pharmacal Research
2012 Volume.35 No. 10 p.1739 ~ p.1747
|
|
|
Phenylpropanoids and lignanoids from Euonymus acanthocarpus
|
|
Zhu Jia Xian
Ren Jie
Qin Jiang Jiang
Cheng Xiang Rong
Zeng Qi
Zhang Fei
Yan Shi Kai
Jin Hui Zi
Zhang Wei Dong
|
|
|
Abstract
|
|
|
|
A new phenylpropanoid derivative (1), along with five phenylpropanoids (2?6), two monoepoxy lignans (8?9), one bisepoxy lignan (10), two cyclolignans (11?12), six neolignans (7, 13?17), two mixed lignan-neolignans (18?19), two lignan glycosides (20?21), and four flavonolignans (22?25), were isolated from the stems and twigs of Euonymus acanthocarpus. Compounds 2?3, 6?8, 12, and 14?25 were obtained from Celastraceae family for the first time, and compounds 5 and 9 were isolated from Euonymus genus for the first time. All the compounds were tested for cytotoxicity against SK-OV-3 and MCG-803 human tumor cell lines. Compounds 3, 10, 12, and 18 showed weak cytotoxicity against SK-OV-3 cell line, and compounds 3?4, 10?13, and 19 showed weak cytotoxicity against MCG-803 cell line.
|
|
|
KEYWORD
|
|
|
Euonymus acanthocarpus, Celastraceae, Phenylpropanoid, Lignanoid, Cytotoxicity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|